A discrimination study of human core-promoters.
نویسنده
چکیده
A core-promoter, approximately from -60 bp upstream to +40 bp downstream of a RNA polymerase (RNAP) II transcription start site (TSS), binds to the preinitiation complex (PIC) and determine the position of TSS. Using position-specific k-tuple feature variables, a quadratic discriminant analysis (QDA) method is shown to be very effective in identifying human core-promoters.
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ورودعنوان ژورنال:
- Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
دوره شماره
صفحات -
تاریخ انتشار 1998